CUSTOM MADE VACCINES

CUSTOM VACCINES

Salmonella

Salmonella enterica is known for serotype variation; poultry flocks are often exposed to 3-5 serotypes or more, out of a group of 20-30 familiar strains. Serotypes such as Heidelberg, Kentucky, Enteritidis, Hadar, Senftenberg and Oranienberg offer very little hope for shared immunity by using conventional whole-cell bacterins. Common autogenous bacterins may contain 2-4 Salmonella serotypes, which results in tissue reactivity, causing local granulomas and sometimes hemorrhagic hepatopathy.

Autogenous SRP® bacterial extract technology offers a new way to approach Salmonella through the immune system. Starting with an isolate of any serotype from your own operation, we can make a purified SRP extract vaccine utilizing proteins which are conserved across all common Salmonella serotypes.

Autogenous SRP vaccines can be made in a variety of adjuvants, dose volumes, pathogen combinations, and routes of administration.

Autogenous vaccines carry no USDA approved label claims for efficacy; therefore use according to the recommendation of your poultry veterinarian.

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E. coli

E. coli peritonitis is a major cause of mortality and production loss in broiler breeders and egg laying chickens. E. coli strain variation from house to house renders conventional killed bacterins impractical for fighting peritonitis.

SRP® technology meets this challenge by targeting a unique class of surface proteins which are commonly found in many strains of E. coli.

Vaxxinova creates Autogenous E. coli SRP Bacterial Extract by screening multiple strains of pathogenic E. coli from your operation, looking for the most prolific producers of SRP proteins. Once the best strain (or two strains) is found, an autogenous SRP extract vaccine is manufactured according to USDA regulations.

Autogenous vaccines carry no USDA approved label claims for efficacy. Therefore, Vaxxinova recommends that autogenous SRP bacterial extract vaccines are used according to the recommendation of your poultry veterinarian.

Autogenous SRP vaccines can be made in a variety of adjuvants, dose volumes, pathogen combinations, and routes of administration.

Publications

Characterization of Escherichia coli Isolates from Peritonitis Lesions in Commercial Laying Hens » Trampel Peritonitis 2007

Pasteurella multocida

Pasteurella multocida is the agent of fowl cholera, an infectious bacterial disease causing mortality in broiler breeder hens and roosters, and egg laying chickens. Vaxxinova US, has been making Autogenous SRP® bacterial extract against P. multocida for breeder turkeys since the late 1990’s.

Because SRP technology is not dependent on serotype, we select autogenous field isolates which produce the best array of commonly shared proteins, regardless of serotype.

Autogenous vaccines carry no USDA approved label claims for efficacy; therefore, use according to the recommendation of your poultry veterinarian. Autogenous SRP vaccines can be made in a variety of adjuvants, dose volumes, pathogen combinations, and routes of administration.

Autogenous SRP bacterial extracts for poultry are available exclusively through Vaxxinova US.

Publications

Vaccination with Siderophore Receptors and Porins Protects against Fowl Cholera Challenge by Heterologous Serotypes » Carver Heterologous Challenge 2017

OTHER AUTOGENOUS VACCINES

Other common custom vaccines are Gallibacterium SRP, coryza whole-cell, erysipelas, and camplyobacter. Connect with us to learn more about these pathogens, as well as bottling sizes and adjuvant options.